9:00 - 11:00 Session 1 Regulation of IF Assembly
and Dynamics in Vivo and in Vitro
Session chairs: Mirjana Liovic, Roy Quinlan
Harald Herrmann: "Principles of Intermediate
Filament Assembly: Keratins to Lamins"
Harish C. Pant: "Topographic Regulation of
Neuronal Intermediate Filament Proteins in Health and Disease"
Roy Quinlan: “Desmin, AlphaB-Crystallin and the Legacy of the
Thomas Dechat: “The Influence of LAP2alpha on the Assembly
Properties of A-type Lamins”
Stephanie Portet: “Mathematical Modelling of IF Assembly”
Marcin Moch: “Computational Analysis of Keratin Network
Dynamics in Response to Epidermal Growth Factor Stimulation and Plectin
11:00 - 11:30 Coffee break
11:30 - 13:00 Session 2 IF Structure, Mechanical
Properties and Mechanotransduction
Session chairs: Marco Biggiogera, Jaroslav Mokrý
Ohad Medalia: "Insight into the Functional
Organization of Lamins"
Norbert Mücke: "Assembly Kinetics and
Mechanical Properties of Cytoplasmic Intermediate Filaments"
Tomas Venit: “Atomic Force Microscopy Reveals Differences in
Cell Membrane Properties in Nuclear Myosin I Mutant“
Balasz Kiss: “Nanomechanics of Desmin Filaments Explored with
Force-Clamp Optical Tweezers“
13:00 - 13:45 FEI
lunch workshops (Diane Van Rossum):
- New Dimensions in 3D Volume Imaging Using Electron
- New Tools for Correlative Light and Electron Microscopy
13:45 - 15:15 Session 3 IF Associated Proteins and
Regulatory Crosstalk in a Cell
Session chairs: Roland Foisner, Klara Weipoltshammer
Gerhard Wiche: "Distinct Roles of Plectin
Isoforms in Skeletal Muscle"
Giovanna Lattanzi: "SUN1 as a Key Player in the Onset of Muscular Dystrophy"
Yassemi Capetanaki: "Μyospryn: a Multifunctional
Tina Zupancic: “The Effects of Ionizing Radiation on Keratin 5
or 14 Mutant Keratinocytes“
15:15 - 16:00
Poster Session / Coffee break
16:00 - 18:00
Session 4 IFs in
Pathology and Diagnostics
Session chairs: Pavel Strnad, Axel Walch
Nam-On Ku: "Caspase
Cleavage-Resistant Keratin 18 Mutation Protects Liver from Apoptosis in
Transgenic Mice" - Histochemistry and Cell Biology Lecture
Diana Toivola: "Keratins as Disease
Modulators in the Intestine and Endocrine Pancreas"
Cheng Fang: “Vimentin Regulates Epithelial-to-Mesenchymal
Transition and Fibroblast Proliferation Involved in the Healing of
Serena Bonin: “Luminal and Basal Cytokeratins in Breast Cancer
Lymph Node Positive Patients as Markers of Disease Progression“
Mirjana Liovic: “The K18 S230T Mutation Displaces Tight Junction
Proteins Claudin 4 and ZO-1 and Results in Increased Paracellular
Joel Nyström: “Keratin Intermediate Filaments as Regulators of
Colon Energy Metabolism“